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But true receptor downregulation through lysosomal degradation requires the cell to synthesize entirely new receptors, a process that takes considerably longer
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( 10.1016/j.ejphar.2017.10.049) [DOI] [PubMed] [Google Scholar] 45.Muskiet MHA, Tonneijck L, Smits MM, Van Baar MJB, Kramer MHH, Hoorn EJ, Joles JA, Van Raalte DH